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ABC transporters and multidrug resistance [[electronic resource] /] / edited by Ahcène Boumendjel, Jean Boutonnat, Jacques Robert
| ABC transporters and multidrug resistance [[electronic resource] /] / edited by Ahcène Boumendjel, Jean Boutonnat, Jacques Robert |
| Pubbl/distr/stampa | Hoboken, NJ, : John Wiley & Sons, c2009 |
| Descrizione fisica | 1 online resource (475 p.) |
| Disciplina |
572/.696
615.1 |
| Altri autori (Persone) |
BoumendjelAhcène
BoutonnatJean RobertJacques, M.D. |
| Collana | Wiley series in drug discovery and development |
| Soggetto topico |
ATP-binding cassette transporters
Drug resistance in cancer cells |
| ISBN |
1-282-36879-6
9786612368790 0-470-49513-8 0-470-49512-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
ABC TRANSPORTERS AND MULTIDRUG RESISTANCE; CONTENTS; PREFACE; CONTRIBUTORS; INTRODUCTION: WHAT IS MULTIDRUG RESISTANCE?; PART I ABC PROTEINS: AN OVERVIEW AND DESCRIPTION OF THE STRUCTURE, GENOME, NORMAL TISSUE EXPRESSION, PHYSIOLOGICAL ASPECT, AND MECHANISM OF ACTION; 1 The P-glycoprotein 170: Just a multidrug resistance protein or a protean molecule?; 2 Multidrug resistance-associated protein (MRP/ABCC proteins); 3 ABCG2: A new challenge in cancer drug resistance
PART II ABC PROTEINS AND ONCOLOGY: EXPRESSION, DETECTION, AND IMPLICATION OF ABC PROTEINS IN HEMATOLOGICAL MALIGNANCIES AND SOLID TUMORS4 Expression, detection, and implication of ABC proteins in acute myeloblastic leukemia; 5 ABC proteins and oncology: Expression, detection, and implication of ABC proteins in solid tumors; PART III ABC PROTEINS AND PATHOGENIC MICROORGANISMS; 6 ABC transporters and resistance to antibiotics; 7 ABC proteins involved in protozoan parasite resistance PART IV MULTIDRUG RESISTANCE (MDR) MODULATION THROUGH INHIBITION OF ABC TRANSPORTERS: DESIGN OF INHIBITORS AND MECHANISM OF ACTION8 Reversal agents for P-glycoprotein-mediated multidrug resistance; 9 Reversal agents of multidrug resistance mediated by multidrug resistance-associated proteins (MRPs); 10 Reversal agents for breast cancer resistance protein (BCRP)-mediated multidrug resistance; 11 Strategies to overcome drug resistance in acute and chronic leukemias; 12 Multidrug resistance reversal in solid tumors PART V BIOLOGICAL AND CLINICAL ASPECTS OF MULTIDRUG RESISTANCE: THE ROLE OF THE TRANSPORTERS AT THE MAIN PROTECTION BARRIERS (ABCB1, ABCC1, ABCC2, ABCG2) ON THE BIOAVAILABILITY OF MANY TYPES OF DRUGS AND MEDICATIONS13 ABC superfamily transporters at the human blood-brain barrier; 14 The role of ABC transporters at the intestinal barrier; 15 Genetic polymorphisms in ABC transporters; PERSPECTIVES; INDEX |
| Record Nr. | UNINA-9910139988203321 |
| Hoboken, NJ, : John Wiley & Sons, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
ABC transporters and multidrug resistance [[electronic resource] /] / edited by Ahcène Boumendjel, Jean Boutonnat, Jacques Robert
| ABC transporters and multidrug resistance [[electronic resource] /] / edited by Ahcène Boumendjel, Jean Boutonnat, Jacques Robert |
| Pubbl/distr/stampa | Hoboken, NJ, : John Wiley & Sons, c2009 |
| Descrizione fisica | 1 online resource (475 p.) |
| Disciplina |
572/.696
615.1 |
| Altri autori (Persone) |
BoumendjelAhcène
BoutonnatJean RobertJacques, M.D. |
| Collana | Wiley series in drug discovery and development |
| Soggetto topico |
ATP-binding cassette transporters
Drug resistance in cancer cells |
| ISBN |
1-282-36879-6
9786612368790 0-470-49513-8 0-470-49512-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
ABC TRANSPORTERS AND MULTIDRUG RESISTANCE; CONTENTS; PREFACE; CONTRIBUTORS; INTRODUCTION: WHAT IS MULTIDRUG RESISTANCE?; PART I ABC PROTEINS: AN OVERVIEW AND DESCRIPTION OF THE STRUCTURE, GENOME, NORMAL TISSUE EXPRESSION, PHYSIOLOGICAL ASPECT, AND MECHANISM OF ACTION; 1 The P-glycoprotein 170: Just a multidrug resistance protein or a protean molecule?; 2 Multidrug resistance-associated protein (MRP/ABCC proteins); 3 ABCG2: A new challenge in cancer drug resistance
PART II ABC PROTEINS AND ONCOLOGY: EXPRESSION, DETECTION, AND IMPLICATION OF ABC PROTEINS IN HEMATOLOGICAL MALIGNANCIES AND SOLID TUMORS4 Expression, detection, and implication of ABC proteins in acute myeloblastic leukemia; 5 ABC proteins and oncology: Expression, detection, and implication of ABC proteins in solid tumors; PART III ABC PROTEINS AND PATHOGENIC MICROORGANISMS; 6 ABC transporters and resistance to antibiotics; 7 ABC proteins involved in protozoan parasite resistance PART IV MULTIDRUG RESISTANCE (MDR) MODULATION THROUGH INHIBITION OF ABC TRANSPORTERS: DESIGN OF INHIBITORS AND MECHANISM OF ACTION8 Reversal agents for P-glycoprotein-mediated multidrug resistance; 9 Reversal agents of multidrug resistance mediated by multidrug resistance-associated proteins (MRPs); 10 Reversal agents for breast cancer resistance protein (BCRP)-mediated multidrug resistance; 11 Strategies to overcome drug resistance in acute and chronic leukemias; 12 Multidrug resistance reversal in solid tumors PART V BIOLOGICAL AND CLINICAL ASPECTS OF MULTIDRUG RESISTANCE: THE ROLE OF THE TRANSPORTERS AT THE MAIN PROTECTION BARRIERS (ABCB1, ABCC1, ABCC2, ABCG2) ON THE BIOAVAILABILITY OF MANY TYPES OF DRUGS AND MEDICATIONS13 ABC superfamily transporters at the human blood-brain barrier; 14 The role of ABC transporters at the intestinal barrier; 15 Genetic polymorphisms in ABC transporters; PERSPECTIVES; INDEX |
| Record Nr. | UNINA-9910830388703321 |
| Hoboken, NJ, : John Wiley & Sons, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
ABC transporters and multidrug resistance [[electronic resource] /] / edited by Ahcène Boumendjel, Jean Boutonnat, Jacques Robert
| ABC transporters and multidrug resistance [[electronic resource] /] / edited by Ahcène Boumendjel, Jean Boutonnat, Jacques Robert |
| Pubbl/distr/stampa | Hoboken, NJ, : John Wiley & Sons, c2009 |
| Descrizione fisica | 1 online resource (475 p.) |
| Disciplina |
572/.696
615.1 |
| Altri autori (Persone) |
BoumendjelAhcène
BoutonnatJean RobertJacques, M.D. |
| Collana | Wiley series in drug discovery and development |
| Soggetto topico |
ATP-binding cassette transporters
Drug resistance in cancer cells |
| ISBN |
1-282-36879-6
9786612368790 0-470-49513-8 0-470-49512-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
ABC TRANSPORTERS AND MULTIDRUG RESISTANCE; CONTENTS; PREFACE; CONTRIBUTORS; INTRODUCTION: WHAT IS MULTIDRUG RESISTANCE?; PART I ABC PROTEINS: AN OVERVIEW AND DESCRIPTION OF THE STRUCTURE, GENOME, NORMAL TISSUE EXPRESSION, PHYSIOLOGICAL ASPECT, AND MECHANISM OF ACTION; 1 The P-glycoprotein 170: Just a multidrug resistance protein or a protean molecule?; 2 Multidrug resistance-associated protein (MRP/ABCC proteins); 3 ABCG2: A new challenge in cancer drug resistance
PART II ABC PROTEINS AND ONCOLOGY: EXPRESSION, DETECTION, AND IMPLICATION OF ABC PROTEINS IN HEMATOLOGICAL MALIGNANCIES AND SOLID TUMORS4 Expression, detection, and implication of ABC proteins in acute myeloblastic leukemia; 5 ABC proteins and oncology: Expression, detection, and implication of ABC proteins in solid tumors; PART III ABC PROTEINS AND PATHOGENIC MICROORGANISMS; 6 ABC transporters and resistance to antibiotics; 7 ABC proteins involved in protozoan parasite resistance PART IV MULTIDRUG RESISTANCE (MDR) MODULATION THROUGH INHIBITION OF ABC TRANSPORTERS: DESIGN OF INHIBITORS AND MECHANISM OF ACTION8 Reversal agents for P-glycoprotein-mediated multidrug resistance; 9 Reversal agents of multidrug resistance mediated by multidrug resistance-associated proteins (MRPs); 10 Reversal agents for breast cancer resistance protein (BCRP)-mediated multidrug resistance; 11 Strategies to overcome drug resistance in acute and chronic leukemias; 12 Multidrug resistance reversal in solid tumors PART V BIOLOGICAL AND CLINICAL ASPECTS OF MULTIDRUG RESISTANCE: THE ROLE OF THE TRANSPORTERS AT THE MAIN PROTECTION BARRIERS (ABCB1, ABCC1, ABCC2, ABCG2) ON THE BIOAVAILABILITY OF MANY TYPES OF DRUGS AND MEDICATIONS13 ABC superfamily transporters at the human blood-brain barrier; 14 The role of ABC transporters at the intestinal barrier; 15 Genetic polymorphisms in ABC transporters; PERSPECTIVES; INDEX |
| Record Nr. | UNINA-9910840786103321 |
| Hoboken, NJ, : John Wiley & Sons, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||